Tuesday, 8 September 2026 Independent · Evidence graded Index Q3 2026
Baseline
Preventive medicine, examined.
Annual membership · San Francisco, US

Biograph

$7,500 to $15,000, per year. Serving US.

Price published Figures checked 2026-09-07 Index Q3 2026 Provider website

What it is

Core membership at $7,500 and Black at $15,000, the difference being a multi-cancer blood test and additional check-ins through the year. Bundles MRI, DEXA, VO₂ max and genetic testing, with CT coronary angiography available. Around $54m raised. The closest US structural analogue to the European outpatient programmes, at four times the entry price of the Berlin equivalent.

Published tiers

Core $7,500
MRI, DEXA, VO₂ max, genetic testing. CT coronary angiography available. No multi-cancer blood test. C Whole-body MRI B Cardiopulmonary exercise test C Genomics and gene panels
Black $15,000
Everything in Core, plus a multi-cancer early detection blood test and additional check-ins through the year. C Whole-body MRI B Cardiopulmonary exercise test C Genomics and gene panels B- Multi-cancer early detection blood test

The evidence behind what it offers

We grade tests, not companies. These are our standing assessments of the modalities this provider offers, and they apply identically to everyone offering them.

Baseline evidence grade C: Mechanistically plausible and widely used, but no trial evidence of net benefit in the screened population.
Whole-body MRI

No randomised trial has shown a mortality benefit in asymptomatic adults, and roughly a third of scanned people receive a critical or unresolved incidental finding.

Baseline evidence grade B-: Promising trial evidence that does not yet reach a hard outcome, or a single registrational study without independent replication.
Multi-cancer early detection blood test

Episode sensitivity of 39.3% across all cancers with 99.6% specificity in PATHFINDER 2. The most defensible blood-based addition available, with mortality benefit still unproven.

Baseline evidence grade B: Consistent evidence of benefit, but from trials with surrogate endpoints, single trials, or strong longitudinal cohorts.
Cardiopulmonary exercise test

Cardiorespiratory fitness carries one of the strongest mortality associations of anything measurable, with no observed upper limit of benefit. The best-evidenced measurement in the category.

Baseline evidence grade C: Mechanistically plausible and widely used, but no trial evidence of net benefit in the screened population.
Genomics and gene panels

Plausible and widely sold, with no trial evidence of net benefit from untargeted sequencing in asymptomatic adults. Best value as a once-in-a-lifetime measurement rather than a recurring one.

How to read the price

Every private programme sells an addition to something you already have. In Germany that something is Check-up 35, free every three years from age 35, covering blood pressure, fasting glucose, a full lipid panel, urinalysis and a consultation. Those are the cheapest high-yield measurements in medicine and a meaningful share of people buying private programmes have never used them.

So the question is never whether Biograph beats nothing. It is what the increment buys. At $7,500 that increment is: MRI, DEXA, VO₂ max, genetic testing. CT coronary angiography available. The modalities in the higher tiers are a different purchase again, and worth separating: Black at $15,000.

Against the free baseline
Check-up 35 €0
Core$7,500
Black$15,000

Least expensive of the 2 comparable entries in the Index.

What to ask before booking

  1. Which tier am I being quoted, and does it contain the modality I am booking for? Biograph publishes per-tier contents, so you can check the answer against its own price page before the consultation.
  2. What proportion of your patients receive an imaging finding that requires further investigation, and who owns the follow-up if mine does? Roughly a third of scanned people leave with something critical or unresolved, and the apparatus around the scan matters more than the scan.
  3. Will I get a full ergospirometry report with a ventilatory threshold, and will it be repeated so I can see whether training changed it? Fitness is the rare measurement that is both strongly prognostic and reliably modifiable, which makes the second test as valuable as the first.
  4. If a finding points somewhere you do not treat, who am I referred to? Diagnosis and therapeutics sitting in one organisation is convenient, and it also keeps more of the interpretive judgement inside the business providing the treatment.
  5. What is the median total invoice, as opposed to the advertised programme price? Additional recommendations after the initial consultation are normal in this category and are not usually in the headline figure.

Profile

Nine attributes across three axes, recorded and not scored. We grade tests, never companies, so there is no total here and no winner: the axes pull against each other, and no provider in the Index holds all nine. A programme priced for annual repetition will not publish deep tier structures, and one that declines routine imaging cannot lead on imaging volume. Read it as a description of what this provider is.

What you can verify before contact

Checkable from the provider’s own site without medical knowledge, and without speaking to anybody.

  • Price published before contact : yes
  • Per-tier contents published : yes

    2 tiers itemised

  • Procedure volume published : no

Clinical structure

How the medicine is organised. These are descriptions rather than merits: a conservative imaging policy and a comprehensive one are both defensible positions.

  • Physician-led throughout : yes
  • Diagnosis independent of treatment : no

    Diagnosis and therapeutics in one organisation

  • Cardiopulmonary exercise testing : yes

    The measurement we grade highest, grade B

  • No routine whole-body imaging : no

    Routine imaging offered, which we grade C

Access

Whether the programme is realistically repeatable, and where you can get it.

  • Priced for annual repetition : no

    A baseline purchase rather than an annual habit

  • Available in more than one market : no

    US only

Nearest comparable programmes
Fountain Life Naples, US CORE (n/p)

Same model, closest entry prices. Compare within kind before across it: a per-visit fee and a per-week residential rate are not the same number. The full table →

Questions this article answers

How much does Biograph cost?
Biograph charges $7,500 per year, rising to $15,000 for its highest published tier. The published tiers are Core at $7,500 and Black at $15,000. Taken from the provider's own price page, checked 2026-09-07.
What is included in a Biograph programme?
Core, $7,500: MRI, DEXA, VO₂ max, genetic testing. CT coronary angiography available. No multi-cancer blood test. Black, $15,000: Everything in Core, plus a multi-cancer early detection blood test and additional check-ins through the year. Biomarker count: 20–30 assessments.
Is Biograph worth it compared with a free statutory check?
Check-up 35 (statutory, Germany) is free and covers the cheap high-yield basics: Physical examination, blood pressure, fasting glucose, total cholesterol with LDL, HDL and triglycerides, urinalysis, a one-off hepatitis B and C screen, and a consultation. What Biograph adds at $7,500 is the layer the statutory system does not fund at all. Its Core tier at $7,500 buys MRI, DEXA, VO₂ max, genetic testing. CT coronary angiography available. The significant addition is a cardiopulmonary exercise test, which carries the highest standing grade we award to anything in preventive screening: cardiorespiratory fitness has one of the strongest mortality associations of any measurable variable, with no observed upper limit of benefit, and it appears in fewer than half the programmes we catalogue. Multi-cancer early detection blood test sits in the higher tiers rather than the entry one, so read the tier rather than the range. Our standing grade for each of these is on this page, so you can see which part of the increment the evidence supports before you decide.
Does Biograph include a whole-body MRI?
Yes, from the Core tier at $7,500 upward. The tiers below it do not include imaging. Our assessment of whole-body MRI screening is grade C: no randomised trial has shown a mortality benefit in asymptomatic adults, and roughly a third of scanned people receive a critical or unresolved incidental finding. A programme that reads the scan alongside bloods, function testing and a physician review on the same day handles that better than an imaging centre working alone.
Who is Biograph best for?
Somebody whose specific question matches what this programme measures. Whoever you are, use your statutory entitlement first: it is free, it covers the measurements with the longest outcome record, and a meaningful share of people buying private programmes have never had it.
How long does a Biograph appointment take?
It is delivered across more than one appointment rather than a single day, so allow for scheduling separate imaging and laboratory visits.
What are the alternatives to Biograph?
On the same model and at the nearest prices: Fountain Life in Naples, US from CORE (n/p). Compare within kind before across it, because a per-visit fee and a per-week residential rate are not the same number. The full comparison across all 16 providers we catalogue is in the Baseline Index.
Where is Biograph located?
Biograph is based in San Francisco, US. It operates as annual membership.

This is a factual record rather than a review. We do not score or rank providers. If a figure here is wrong, send the published page that contradicts it and we will correct it and log the correction. Corrections policy.